Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment 4-10 with modifications. With the molecular formula C₃₇H₅₁N₉O₁₀ and a molecular weight of 812.9 g/mol (CAS: 80714-61-0), Semax consists of the sequence Met-Glu-His-Phe-Pro-Gly-Pro with an N-terminal proline and C-terminal glycine-proline added.
Pro-Gly-Pro-Glu-His-Phe-MetAshmarin et al. (2006) investigated Semax's effects on BDNF expression and TrkB receptor activation in neuronal cell cultures (PMID: 16445185).
PMID: 16445185VERIFY PMIDMedvedeva et al. (2008) characterized Semax's effects on gene expression profiles and neurotrophic factor production in brain tissue models (PMID: 18841466).
PMID: 18841466VERIFY PMIDSemax increases brain-derived neurotrophic factor expression and activates TrkB receptors in neuronal cultures (PMID: 16445185).
Research demonstrates Semax modulates expression of genes involved in neuroplasticity and neurotrophic factor production (PMID: 18841466).
All compounds are sold strictly for laboratory research use. Not for human or animal consumption. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.
